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To keep the spare out of the interior where it is taking up valuable space, install a hitch with a fold-down bike rack. Install studs on the bike rack that match the bolt pattern of the spare. You may only want to use this set up for long trips when finding a replacement tire is uncertain.

I do not find carrying a spare tire strapped down in the back a workable solution when there is a need to haul luggage and other gear. Install a bumper hitch with a fold down bike rack. Adapt the bike rack with threaded studs to fit the lug pattern of either a space-saver or full size spare. The rack will fold down allowing the lift gate to be opened. You have the option of only using this set up when traveling on a trip where finding a replacement tire is uncertain.