So what size charger do you have? If your battery has 0% SOC <= 10.5 V by definition (8.5V) and if you charged for one hour and SOC = 100% as you say, then the charger had to put out 43 A for one hour. 100% SOC = 43 Ah for the BXT67R Motorcraft battery. Because your battery is around 5 years old (2015 MY?), it’s maximum capacity will be less than 43 Ah. You got 12.1 V after allowing surface charge to drain which is a maximum SOC of around 30% +- maybe 10% depending on load on battery when you checked voltage. This would mean that if you charged for one hour you likely added between 8 - 16 Ah of capacity (8-16 A charger) to your battery. IMO, this is normal for a 5 year old battery. See attached discharge curve. C = 43 Ah, so the C /20 discharge curve is likely the one to use when measuring battery voltage. Just opening doors activates modules and puts load on battery.
Driving the C-Max adds little to the SOC of the battery. In 25 minutes of driving you will likely add less than 2 Ah and more than likely around 1 Ah. So, best case is you might have increased SOC around 5%. Normal car off battery drain should be less than 50 mA. So if car is off for four days, normal max. drain would be around (96 h x 0.050 A) = 4.8 Ah (should be less unless there is a parasitic drain). I believe around 30 mA would be typical. Thus, the four day Ah drain would be around 3 Ah. This 3Ah drain is still greater than the charge put back in 25 minutes of driving.